Civic administration Anantapur Municipal Corporation is the civic body of Anantapur.
Neelam Sanjiva Reddy was the former President of India and the first Chief Minister of Andhra Pradesh, Paidi Lakshmayya was the first member of Parliament from Anantapur lok sabha constituency; Kallur Subba Rao was an Indian freedom activist and was the first speaker of Andhra Assembly; Tarimela Nagi Reddy Comrade, Indian Communist Revolutionary Movement, Kadiri Venkata Reddy was an Indian film director, writer and also a producer, Sathya Sai Baba, a Hindu spiritual leader; Bellary Raghava was an Indian playwright, thespian and film actor.
Anantapur is an important education centre of the district which has many schools, colleges and universities.
Prominent institutions and universities include, Sri Krishnadevaraya University, JNTU Anantapur, Sri Sathya Sai University, Government Medical College, Srinivasa Ramanujan Institute of Technology etc.
It was also the headquarters of the Datta Mandalam (Rayalaseema districts of Andhra Pradesh and Bellary district of Karnataka) in 1799.
It was also a position of strategic importance for the British Indian Army during the Second World War.